SelenoPrecise® 100 μg
- Unique (patented) organic high-selenium yeast with a wide range of selenium species including Se-methylselenocysteine as found in natural garlic
- For a well functioning immune system*
- Documented in more than 40 published studies, including the groundbreaking KiSel-10 study1
- Documented stable bioavailability of 88.7% for every batch
- Manufactured under pharmaceutical standards and inspected by "the Danish Food and Drug Administration"
SelenoPreciseTM 100 μg
- What is SelenoPrecise?
- What is Selenium?
SelenoPrecise contains pharmaceutical-grade selenium in the form of a unique (patented) organic high-selenium yeast with a wide range of selenium species including Se-methylselenocysteine as found in natural garlic. The body's absorption of this specific selenium yeast (SelenoPrecise®) has been documented at 88.7% absorption in the body. SelenoPrecise's efficacy is documented in more than 40 published studies, including the groundbreaking KiSel-10 study1 that was published in The International Journal of Cardiology (2013).
Selenium is a vital trace element that helps maintain good cardiovascular health, a healthy immune system and good reproductive capability, just as it also protects cells against potentially harmful, tissue-scavenging molecules known as free radicals.* Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer. However, the FDA has determined that this evidence is limited and not conclusive.
SelenoPrecise is Pharma Nord’s potent and patented selenium yeast. It consists of small, round white tablets each containing 100 micrograms of selenium in the form of an organic source of highly absorbable selenomethionine and more than 20 other organically bound selenium compounds. The preparation is unique in the sense that it emulates the various selenium compounds, we get from selenium rich food and is able to document a very high level of bioavailability and a stable quality:
- 88.7% of the selenium content is absorbed in the body
- 15 laboratories in 12 different countries have measured a 67%
L-selenomethionine content in SelenoPrecise
More than 40 scientific studies have been published dealing with product quality, the stable 81% I-selenomethionine content, the high level of bioavailability, and the safety of SelenoPrecise. This is what makes the preparation an extremely well-documented source of selenium. Moreover, it is the main reason why SelenoPrecise is used in scientific studies and research projects worldwide.
Why so many Selenium Species in SelenoPrecise?
SelenoPrecise contains many different selenium species because each type of selenium has a different function in the human body. By supplying a wide spectrum of selenium types it is possible to emulate the natural variety of selenium types, found in food containing selenium. This, scientists believe, has the best effect on our health, and this is why SelenoPrecise is an excellent source of more than 20 different selenium compounds.
SelenoPrecise is the Best Documented Selenium Preparation as a result of our commitment to internal documentation and our willingness to participate in clinical studies worldwide.
SelenoPrecise is substantiated with respect to scientific evidence of stability, safety and bioavailability.
SelenoPrecise is the only selenium tablet with a documented steady absorption rate of 88.7% for every batch. SelenoPrecise has a stable content of 67% organically bound selenium in the form of L-selenomethionine. Moreover, SelenoPrecise contains selenium-methyl-selenocysteine and more than 20 other organic selenium sources, each of which has a different function in the body.
Official Science Reference Product
Pharma Nord has a patent on the raw material used in SelenoPrecise. Because of its quality and documentation, SelenoPrecise is used in clinical trials and research. SelenoPrecise is the European reference product for selenium-enriched yeast.
Selenium is not Just Selenium
Selenium is a trace element and a mineral existing in the soil in varying amounts. In the US, much of the agricultural soil has a relatively high selenium content while it is relatively low in other countries, such as China and various European countries. Corn and other plants absorb selenium from the soil and pass organic selenium on to the animals and human beings that ingest the corn/plants. Human dietary selenium content therefore depends largely on the amounts of selenium supplied to the crops and vegetables by the soil.
An Important Mineral
Selenium is essential in a number of important hormonal and physiological functions in our body. Among other things, selenium is necessary for a normally functioning immune system, thyroid function, production of sperm cells, normal hair and nails, and selenium also protects the body's cells against oxidative stress.
Selenium products often consist of inorganic selenium in the form of simple selenium salts like sodium selenite and sodium selenate. Inorganic selenium is normally insoluble in water, but selenium in the form of selenite and selenate is soluble in water. Just over half of these two inorganic selenium salts is absorbed into the body, selenite somewhat more easily than selenate, but these selenium salts are also excreted fairly rapidly, which contributes to limiting the body's ability to use them.
Plants absorb inorganic selenium from the soil in the form of selenate. When the selenium is incorporated into the plants as selenomethionine and to a lesser degree as selenocysteine, it becomes organic selenium. The organic selenium compound L-selenomethionine can also be prepared synthetically. It is selenium attached to the amino acid methionine. Synthetic L-selenomethionine is widely used as an organic selenium supplement and is among the most studied selenium compounds.
Selenium-enriched yeast comes from yeast cells, which have been cultured in a selenium rich growth medium. This method of production gives a high content of naturally occurring organic L-selenomethionine. Selenium yeast also contains methylselenocysteine and a variety of other organic selenium compounds that emulate the natural selenium variation in our diet. Scientific studies show that it is important to have naturally occurring organic L-selenomethionine, methylselenocysteine, and other organic selenium compounds in a selenium supplement. The yeast is subsequently inactivated by heating processes, and, thereafter, the product becomes a selenium-rich carbohydrate.
Differences in the Quality of Selenium Yeasts
There are differences in the quality of various selenium yeast products. A non-standardized selenium yeast will typically have relatively large variations in the quantity of the various selenium compounds it supplies. This implies that the bioavailability can vary greatly. The selenium yeast products that provide a consistent and balanced selenium source are produced under pharmaceutical-grade production standards and have insignificant variations in the type and quantity of their various selenium compounds.
EU's Best-Documented Selenium Product
Many people take selenium supplements daily, but they are perhaps not aware of the large differences in quality and bioavailability in the different dietary supplements.
If you are not sure whether you are using the right product, you can try to test your current selenium tablet against SelenoPrecise - the best-documented selenium tablet.
Compare Your Current Selenium Product to SelenoPrecise®
|Over 20 years of user experience in EU||Yes||?|
|Scientific evidence for bioavailability||Yes||?|
|Scientific data on safety||Yes||?|
|Scientific evidence of efficacy||Yes||?|
|Selected as European reference product for selenium-enriched yeast||Yes||?|
|Produced exclusively in Denmark under cGMP and under pharmaceutical control by the Danish authorities||Yes||?|
|Contains more than 20 organic selenium compounds, with the most dominant being L-selenomethionine||Yes||?|
|Bio-identical selenium compounds - i.e. the same types found in the selenium-containing foods||Yes||?|
|Tested and documented in 50 scientific studies||Yes||?|
|Patented product formulation||Yes||?|
|Used daily by thousands of consumers in more than 40 countries||Yes||?|
|Has a stable, uniform quality, which does not differ from production batch to the next||Yes||?|
|Is guaranteed to be manufactured under pharmaceutical control exclusively at our plant in Denmark in accordance with manufacturing regulations established by the Danish authorities||Yes||?|
Selenium is an essential trace element that supports an array of selenoproteins and selenium-dependent enzymes that are important for human health and well-being. One of these enzymes is glutathione peroxidase (Gsh-Px), which has several important antioxidant functions in the body. In addition, selenium supports a normal thyroid function. The thyroid function helps maintain a balanced metabolism. Furthermore, selenium supports biological processes such as:
- a normal immune system*
- production of normal sperm cells*
- cell protection*
- the maintenance of normal hair and nails*
Most of the Selenium in the Body is found in Two Forms:
Selenomethionine (that is embedded in different proteins rather than in methionine) and selenocysteine.
We humans obtain selenomethionine exclusively from the diet because the body is unable to synthesize it. The body is, however, able to convert selenomethionine to selenocysteine, which we are also able to get from the diet in the form of se-methylselenocysteine.
When our diet provides us too little selenium, our body is able to use selenium that is stored in the body, simply by converting selenomethionine that is bound to different proteins.
SelenoPrecise contains both of these main selenium sources (selenomethionine and selenocysteine) plus several other selenium compounds.
The Ability of Selenium to Bind to Heavy Metals
In the body, selenium binds to different heavy metals such as mercury and cadmium and forms insoluble compounds that are eventually discharged from the body. This process consumes some of the available selenium, leaving less for other important selenium-dependent processes2 Studies show that selenium binds to mercury in a 1:1 ratio.
Where is Selenium Found?
You can obtain selenium from fish, nuts and whole-grains. People who do not consume these food items regularly may benefit from taking selenium as a dietary supplement to ensure that the body has sufficient amounts available for its physiological processes. The Recommended Daily Value (DV) for selenium is around 70 μg for adults.
Organically Bound Selenium has Higher Absorption
Selenium in the soil is inorganic. Once plants absorb it, selenium gets converted into organic selenium. The selenium we obtain from our diet can be bound to amino acids such as methionine and cysteine. Selenium supplements can either be organic or inorganic. It is known that organic selenium compounds have an easier time getting absorbed in the body and incorporated into the different selenium-dependent enzymes and selenoproteins.
|1 Tablet contains||DV *|
|Selenium (as Organically Bound Selenium-Enriched Yeast SelenoPrecise**)||100 µg||143%|
* DV = Daily Value.
** EP Patent No. 1 478 732 B1.
Take one (1) tablet 1 to 2 times daily or as directed by your qualified healthcare professional. To be taken with a meal.
Do not exceed recommended amount.
Pregnant and lactating women and those on medication should consult their healthcare professional before use.
Suitable for vegans and vegetarians.
Microcrystalline cellulose, dicalcium phosphate, silicon dioxide, hydroxypropyl methylcellulose, talc, magnesium stearate (vegetable source), titanium dioxide (color).
Room temperature and out of direct sunlight. Keep out of reach of children. Use by date printed on flap.
** EP Patent No. 1 478 732 B1.
Organic Selenium with 88.7 Percent Bioavailability
SelenoPrecise® is a unique, organic selenium source, which contains more than 30 organic selenium compounds. SelenoPrecise® was selected and administered by researchers in the KiSel-10 clinical trial, a double blind placebo-controlled, randomized trial with 443 healthy elderly subjects.
After 4 years' supplementation, the results showed a significant effect, in addition to a general improvement in the quality of life in the experiment group taking SelenoPrecise® and Bio-Quinone Active CoQ10.*
The results were published in The International Journal of Cardiology, 167 (5), 2013.
- Alehagen U, Johansson P, Björnstedt M, Rosén A, Dahlström U. “Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation”: a 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. Int J Cardiol. 2013 Sep 1;167(5):1860-6. doi: 10.1016/j.ijcard.2012.04.156. Epub 2012 May 23.
- Schrauzer GN Selenium and selenium-antagonistic elements in nutritional cancer prevention. Crit Rev Biotechnol. 2009;29(1):10-7.
Pharma Nord's Patented Selenium Yeast approved by EFSA
Pharma Nord's selenium yeast SelenoPrecise® is a highly bioavailable, standardized selenium yeast.
Please read the safety assessment from EU's scientific experts EFSA of the source of selenium yeast used by Pharma Nord: Click here!
PubMed Study Links
Bio-Quinone Active CoQ10 Gold has been in more than 100 clinical trials, 75 of which are human clinical trials and 25 being Gold Standard clinical trials. Below are some of the more recent clinical trial statistics from the US National Library of Medicine at the National Institutes of Health:
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.